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EMCrit Project

Online Medical Education on Emergency Department (ED) Critical Care, Trauma, and Resuscitation

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IBCC – Acute Liver Failure

March 8, 2021

IBCC – Spontaneous Bacterial Peritonitis

March 6, 2021

EMCrit 293 – The Jerk & Check, Functional Heuristics in Resuscitation Project (MotR)

March 3, 2021

Still Super Fresh

IBCC – Invasive candidiasis

March 1, 2021

EMCrit 292 – IV T3 for Myxedema Coma, A Different Take with Eve Bloomgarden

February 23, 2021

IBCC – Hepatorenal Syndrome

February 22, 2021

IBCC – Coagulation management in cirrhosis

February 15, 2021

All the Rest

PulmCrit – RECOVERY confirms benefit of toci combined with dexamethasone

The RECOVERY trial just released a preprint demonstrating benefit from tocilizumab in COVID-19.  As with the prior RECOVERY studies, this is a multicenter, open-label, pragmatic trial.  A robust mortality benefit was detected (the fragility index calculates to 17, which isn’t too shabby).  Several important secondary endpoints were positive as well (e.g., reduced intubation rate, reduced […]

EMCrit 291 – For Frak’s Sake, Ketamine is at least as Hemodynamically Stable as Etomidate!

Ketamine IS AT LEAST as hemodynamically stable as ETOMIDATE!!!

IBCC chapter & cast – Atrial Fibrillation in critical illness

Most available data on atrial fibrillation pertains to chronic outpatient management or atrial fibrillation following cardiac surgery.  This data may not apply perfectly to most critically ill patients.  Extrapolation of available data to the management of critically ill patient is challenging, with much left to clinical judgement. The IBCC chapter is located 👉 here. The […]

PulmCrit Wee – MENDS2: Fentanyl or fentanyl for sedation in mechanically ventilated adults with sepsis

The MENDS2 trial was intended as a study comparing dexmedetomidine to propofol. However, the doses of these medications used in the study weren’t high enough to be impactful. In retrospect, the study may actually be an investigation of how clinicians approach the agitated intubated patient – potentially revealing an over-reliance on opioid infusions.

PulmCrit Wee – Follow-up Bamlanivimab study unmasks statistical chicanery

Whether or not you have any interest in bamlanivimab, you should read this post as an amusing example of shoddy statistics being published in top journals.  background & general landscape of the two trials The BLAZE-1 trial involved randomizing patients within three days of testing positive for COVID-19 to one of four arms:  placebo, 700 […]

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