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EMCrit 253 – Kovacs Kata to Optimize a Failing Laryngoscopy Attempt
dedicated to my friend, George Kovacs
IBCC chapter & cast – Septic Shock
Septic shock is perhaps the defining illness of medical intensive care. As such it is an enormously broad and controversial topic. This chapter attempts to provide a unified and straight-forward approach. However, every physicians has a different approach to septic shock, so it’s impossible to claim that this is the best approach. There will doubtless […]
Tox and Hound – Some Like It HOT
by Dan Rusyniak Stimulant-Induced Hyperthermia, a (sort of) memoir. I will admit my biases up front. This post is based primarily on my own research or the research of people I have collaborated with. There may be other viewpoints out there, but I will stick with what and who I know. If someone disagrees with […]
IBCC chapter & cast – Angioedema
Like so many things in critical care, angioedema is difficult to research since it is uncommon, heterogeneous, and emergent. As such, we have relatively little high-quality evidence regarding this disease (and the high-quality evidence that we do have is largely restricted to pharma-sponsored trials of new and insanely expensive pharmaceuticals). This chapter attempts to create […]
PulmCrit Wee: Reconceptualizing bradykinin-mediated angioedema as a universal vicious spiral
In 2015 I wrote this post on ACEi-induced angioedema. I still think it was a pretty good post (particularly for 2015), but it’s become increasingly clear recently that the post was fundamentally flawed. Let’s try to straighten this out. old model of bradykinin-mediated angioedema This is a conceptual model of how bradykinin-mediated angioedema occurs. Several […]
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