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IBCC – Purpura Fulminans
Purpura fulminans is a rare form of disseminated intravascular coagulation which requires specific management. Most commonly it is seen as a complication of septic shock with multi-organ failure. Unfortunately, purpura fulminans is often treated simply with a generic approach for septic shock. The IBCC chapter is located 👉 here. The podcast & comments are below. […]
Tox and Hound — Happy New Year!
All of us at the Tox and the Hound want to thank you, dear readers, for continuing to stick with us on this incredible and strange journey. While we haven’t been with you as much as we’ve liked, there still has been an exciting range of topics covered. We kicked off the year with the […]
PulmCrit – Baricitinib for COVID-19: The rise of the jakinibs
Background: JAK-inhibitors (jakinibs) in the greater context Much of the harm from infections is mediated by hyperactive inflammatory reactions. To date, most research has focused on two classes of medications to treat this: Corticosteroids have the advantage of being cheap, widely available, and often effective. The disadvantage is that corticosteroids modulate innumerable molecular pathways, thereby […]
EMCrit 288 – Neurogenic Shock & Should we be Using Vasopressors for Hemorrhagic Shock?
Neurogenic Shock and Vasopressors for Hemorrhagic Shock
The Dantastic Mr. Tox & Howard – S03E04 – For The Greater Good
”Just a Pandemic” . . . Scorpion prevention, Women In Toxicology, mentorship, and pharmacogenetics with Dr. Ayrn O’Connor. Welcome home, listeners! Sit back, relax, and join Dan (@drusyniak) &Howard (@heshiegreshie) as they learn how to prevent scorpions from coming home, explore pharmacogenetics, and explore the incredible importance of mentorship, representation, diversity, and equality with Dr. […]
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