People on twitter absolutely hate the concept of using a central line to resuscitate a GI bleeder. This comes up a couple times per year.
I think the source of this hatred is largely three-fold:
- A central line alone is garbage (without a Level-1 or Belmont infuser). I'll admit that. So if you're working in a place without immediate access to a fancy pressure infuser then yeah – don't use a central line.
- The approach to GI bleeding is based on the approach to massive hemorrhage in trauma – which is a different disease process that involves different treatments (e.g., emergent open surgery).
- Machismo (“when I admit a GI bleeder, I crack open the chest and sew a garden hose directly into the right atrium”).
I work at a GI bleed center of excellence and I've resuscitated a lot of severe GI bleeders using a central line plus a Belmont infuser. This can get in one round of massive transfusion (6 PRBC, 6 FFP) in roughly five minutes. And that's completely fine for nearly all severe GI bleeders:
- Hypotension in GI bleed is usually because the patient has been slowly losing blood for several hours and they're way behind. You need to catch up, but whether you catch up over 2 minutes or five minutes doesn't really matter.
- Infusing blood products at a much faster rate isn't necessarily a great thing. I've seen some patients deteriorate after running massive transfusion through dialysis catheters. There is a risk of over-pressurizing the venous system, leading to venous congestion and endothelial damage. Slamming in ginormous amounts of blood at lightning speed is flashy, but I'm skeptical about whether it actually helps the patient.
- If the patient is truly losing blood at such a fast rate that a central line plus Belmont can't keep up (ongoing hemorrhage at >~1 unit/minute), it's dubious whether any intervention in the ICU will be able to manage this. For example, the patient could easily exhaust the entire hospital's blood supply en route to the angio suite. This is an incredibly rare situation that I've seen maybe once (aortoenteric fistula with exsanguination over minutes).
A central line has the following advantages, which almost no other line has:
- It's secure (will not fall out during transport, or kink off if the patient bends their neck).
- Gives you multiple lumens (to run pressors, calcium, products) – we love our quad-lumen lines in ICU.
- Combined with a Belmont infuser it achieves an adequate flow rate.
- It's readily available (doesn't require rummaging around in the supply room).
- It is pressure injectable, allowing for the performance of CT angiography.
This last point is really important. If the gastroenterologist fails to control the bleed, the next step is often CT angiography in preparation for interventional radiology intervention. This involves pressurized injection of contrast dye – which must be performed via an 18g peripheral IV or a device that is specifically rated as pressure injectable (so it won't explode under pressure):
- Ideally, all central lines at your shop will be pressure injectable.
- Cordis catheters/sheaths aren't pressure injectable (I once insisted on doing a CT angio through one and… yeah, it completely exploded).
- MAC catheters don't appear to be pressure injectable (at least they aren't labeled as such).
So in conclusion, I feel like a quad-lumen pressure-injectable central line is the Toyota Accord of GI bleed resuscitation. It's not the fastest nor the flashiest option. But it's a solid option that gets the job done.
I'm sure that this post won't end the debate about vascular access for GI bleeds. Maybe it doesn't apply to the context where you practice critical care. But I do think that we need to be more open-minded about using different access approaches for gastrointestinal hemorrhage.
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I like to use non-tunneled dialysis catheters. I get three lumens, 2 large bore and a pigtail for meds.
how can we overpressurize a system that has excellent compliance and is collapsed. Isnt this trying to spend money on a product that is not needed.
Just gave our fellows a lecture on GIB resus last week and took the same stance. The 16G distal lumen of your triple lumen CVC is NOT going to be the limiting factor in your GIB resus. with using a Level 1 transfuser. Arrow claims max flow rate for this lumen at 6.2L/hr for saline. Even if blood flow was half that at 3.1L/hr thats ~10units in 1 hour and probably between 50-100% of their blood volume depending on their size. If thats not cutting it then like Farkas says probably doesn’t matter what access you have your not gonna… Read more »
Calling it a Toyota Accord was a bit painful to read – it’s a Honda Accord!!!
Thank you for the great wee and all of your work. I’ve had multiple e-mail discussions with our Teleflex rep (manufacturer of the MAC) and they confirmed that the MAC is NOT pressure injectable. They also confirmed that the single/multiple infusion catheter (SLIC) that can be placed into the MAC are not pressure injectable. Looking at their website now it looks like they have triple lumen CVCs for high volume infusions that has 1 16 ga and 2 12 ga lumens rated for 12.6 L/hr but these are also appear to not be pressure injectable.
I’m confused about the pressure injectable thing and the explosion part. What explodes? The contrast or the catheter itself? Why would such a thing happen?
Hey Josh, I like the concept you’re going for here and going against the grain. But the math just simply doesn’t seem to pan out. If you’re using the distal (brown) port on the triple-lumen, it’s a 16G but due to length roughly equivalent to a 20G peripheral. Max Flow rate of crystalloid under pressure is roughly in the neighborhood of 140 mL/min (and that’s pushing it) You’re saying you get 12 units (6 PRBC + 6 FFP) of product delivered in 5 mins? Let’s just call it avg 300mL/unit product x 12 = 3,600 mL If we do the… Read more »