Quantitative waveform capnography is rapidly becoming a standard of care for any intubated patient. Although this may appear simple, it provides a host of information about ventilation and cardiac output. When further integrated with clinical context (such as trends in minute ventilation), there is a potential for fundamentally changing how we monitor our patients. If we are willing to embrace zentensivism and accept some error in our estimation of the patients pCO2, this may allow for substantial reductions in blood gas measurements.
-
The IBCC chapter is located 👉 here.
- The podcast & comments are below.
Follow us on iTunes
- PulmCrit – 2025 AHA & ESICM guidelines on post-arrest care - October 26, 2025
- PulmCrit: 6 pearls on HIT (heparin induced thrombocytopenia) - October 4, 2025
- PulmCrit Blog: Nalbuphine, the Diet Coke of opioids - September 8, 2025

Great review! Only editorial comment is that targeting “normal” PaCO2 in a pregnant patient, will result in relative hypercapnia, as normal PaCO2 in pregnant women generally lies in the low 30s mmHg from the end of the first trimester on. (The text says target 35-45).
Hello,
This is such an interesting article, i really liked the aticle.
Time spent reading this is really great.
keep it up!