Acute promyelocytic leukemia (APL) is a unique leukemia, with particular importance to resuscitationists. Unlike most leukemias, the highest rate of mortality occurs at the time of diagnosis (a phenomenon known as “early deaths”). If patients are able to survive the initial phase of illness, the cure rate is extremely high (>90%). Aggressive support in the initial phase of illness is therefore of utmost importance. The disease poses some unique challenges, but these are predictable and fairly manageable.
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Josh is the creator of PulmCrit.org. He is an associate professor of Pulmonary and Critical Care Medicine at the University of Vermont.
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