Acute on Chronic Liver Failure (ACLF) refers to decompensated cirrhosis causing failure of at least two organs (e.g. hepatic encephalopathy, hepatorenal syndrome, shock, or respiratory failure). It may be useful to conceptualize these patients as having ACLF (rather than, for example, hepatic encephalopathy plus hepatorenal syndrome), because this provides a more accurate global understanding of the patient. Additionally, labeling patients as ACLF may promote a more comprehensive approach to their care, which focuses on preventing other cirrhosis-related complications.
The IBCC chapter is located 👉 here.
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