Cite this post as:
Scott Weingart, MD FCCM. EMCrit 261 – Thrombolysis during Cardiac Arrest. EMCrit Blog. Published on December 12, 2019. Accessed on June 6th 2023. Available at [https://emcrit.org/emcrit/thrombolysis-cardiac-arrest/ ].
Dr. Scott Weingart, Course Director, reports no relevant financial relationships with ineligible companies.
This episode’s speaker(s), (listed above), report no relevant financial relationships with ineligible companies.
Original Release: December 12, 2019
Date of Most Recent Review: Jan 1, 2022
Termination Date: Jan 1, 2025
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Do you still do the 50 mg alteplase dose in cardiac arrest stemi? Or do you do the AHA 50 mg bolus followed by infusions of 15mg and 35mg?
50 mg followed by cath lab
Hey Scott, What does “continued resuscitation” mean in your shop? Are you continuing to give Epi every 5 and doing rhythm checks after administering lytics?
Hi Scott, do you happen to have any good references confirming the utility (or lack there of, as you suggest) of RV morphology during cardiac arrest as it relates to PE? I only know of one paper out of UCSD on the overall high prevalence of RV dysfunction peri-arrest and some data out of Denmark on animal models.
Very much appreciate that, thank you! If interested, to add to that list is the UCSD article I mentioned: https://www.ncbi.nlm.nih.gov/pubmed/27079665
Scott, im writing from Trujillo – Perú.
I want to ask you maybe want to come to my country for a congress….
do you give the patient anticoagulation (e.g. UFH) during CPR after the application of thrombolysis?
I could not find anything conclusive on the issue, rather some sidenotes, that in some studies they gave anticoagulants as well as thrombolysis.
Even though it would make pharmacological sense (you dissolve a clot and want it to NOT form again), there is no recommendation I could find and I have to ask myself about the increased bleeding risk vs benefit (which we know about from studies done on lysis in MI combined with Heparin)…
Thanks a lot!