A perfect trial would require minimal statistical tools to assist in its analysis. Such a trial would be so large that the sample approached the true likeness of the broader population it intended to emulate, thus the risk of sampling error would be minimal. The confidence intervals surrounding the point estimates would be so minute, […]
EMNerd
The Nihilistic Ramblings of Rory Spiegel, MD
EM Nerd-An Addendum to the Case of the Non-inferior Inferiority
Until recently the management of acute appendicitis has lay squarely in the hands of the surgeon. But there is a growing body of evidence examining the use of antibiotics alone in uncomplicated appendicitis. Most of the data exploring this question has found that the majority of patients treated with antibiotics alone will avoid surgery in […]
EM Nerd-The Case of the Anatomic Heart Revisited
If Maslow were to generate a hierarchy of needs to assess the utility of the coronary CT angiogram (CCTA) in the Emergency Department for the evaluation of chest pain it would look something like this: We have fairly robust data demonstrating the use of CCTA does not improve mortality, nor does it decrease the rate […]
EM Nerd-The Case of the Erroneous Humour
Since the NEJM publication by Pope et al in 2000 found 2% of patients with myocardial infarctions were discharged home from the Emergency Department, we have been in search of a tool capable of identifying a cohort of patients who are truly safe for discharge1. Many have anointed the high-sensitivity troponin assay (hs-cTnI) to this […]
EM Nerd-The Case of the Needless Imperative
Airway has been paramount to the management of cardiac arrest since the earliest endeavors in resuscitation. The use of tobacco smoke enemas to resuscitate drowning victims on the banks of the Thames was documented as far back as 17461. Such efforts while anatomically misplaced, were in principle well intended. Although, we have since discovered alternative […]