Tumor lysis syndrome isn't encountered very often in critical care, but we will see the most extreme extent of this illness. Within the last decade, rasburicase has been a game-changer here. Understanding some basic physiology will guide the optimal diagnosis and treatment of tumor lysis syndrome in the post-rasburicase era.
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The IBCC chapter is located here.
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Hey, how low would you be happy to run the calcium? Just had a patient whose iCa was around 0.8. Calcium was the only thing that made much of a difference to the significant hypotention this patient faced (pH 6.6!) but the effect did not last long.