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EMCrit Project

Online Medical Education on Emergency Department (ED) Critical Care, Trauma, and Resuscitation

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You are here: Home / Archives for plasmalyte

The SPLIT trial: Internal vs. external validity

October 11, 2015 by Josh Farkas 4 Comments

. Introduction . Resuscitation with large volumes of normal saline (NS) causes hyperchloremic metabolic acidosis.  Some evidence suggests that hyperchloremic metabolic acidosis may impair renal function, but the clinical relevance of this remains unclear.  If hyperchloremic metabolic acidosis is truly detrimental, this would be one argument to use balanced crystalloids rather than NS.  . . […]

Three myths about Plasmalyte, Normosol, and LR

January 26, 2015 by Josh Farkas 13 Comments

0 Introduction: Selecting the best balanced crystalloid 0 About six months ago, Genius General Hospital added Normosol to its formulary.  For those of you not familiar with Normosol, it is produced by Hospira and is essentially a generic version of Plasmalyte by Baxter (table below).   Although most evidence has been obtained with Plasmalyte, this is […]

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