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Online Medical Education on Emergency Department (ED) Critical Care, Trauma, and Resuscitation

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You are here: Home / Archives for non-inferiority

EM Nerd-The Case of the Adjacent Contradictions

December 23, 2019 by Rory Spiegel 6 Comments

There has been a long-standing debate in the fields of emergency medicine and critical care regarding the ideal paralytic agent to use during RSI, rocuronium or succinylcholine. This dispute, has even developed slogans such as Roc Rocks, Sux Sucks as one side attempts to definitively proclaim its superiority through witty aspersions. But up until now […]

The Case of the Scientific Ruse

February 11, 2019 by Rory Spiegel 18 Comments

February 7th 2019 marked a auspicious day in the history of the NEJM and its relationship with the pharmaceutical industry. In 2015, the NEJM shifted their significant weight in support of a strong union between industry and medicine1,2,3. With the simultaneous publication of four pharmaceutical sponsored trials, each brimming with its own unique form of […]

EM Nerd-The Case of the Inferior Superiority

October 18, 2018 by Rory Spiegel 11 Comments

A perfect trial would require minimal statistical tools to assist in its analysis. Such a trial would be so large that the sample approached the true likeness of the broader population it intended to emulate, thus the risk of sampling error would be minimal. The confidence intervals surrounding the point estimates would be so minute, […]

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