by Sarah Shafer How does a heart break? In the case of beta-blocker (BB) and calcium-channel blocker (CCB) overdose, it’s a lack of calcium. Calcium is essential to muscle contraction, allowing actin and myosin to interact so that the cell shortens. Without calcium, the myosin and actin are blocked from interacting, and the cell stays […]
Chris Nickson, one of my favorite EM bloggers, wrote with some great additional resources on calcium channel blocker overdose.