Cellular Efflux of Protons and Lactate Steven C Curry, MDUniversity of Arizona College of Medicine – PhoenixBanner – University Medical Center PhoenixPhoenix, AZ@SteveCurryMD Robert A Robergs, Ph.D.School of Exercise and Nutrition Sciences, Faculty of HealthQueensland University of TechnologyBrisbane, QLD, Australia As noted in the comments in the post on the origins of protons in lactic […]
Tox and Hound – Fellow Friday – Whence the Protons of Lactic Acidosis?
Whence the Protons of Lactic Acidosis? The case of impaired mitochondrial electron transport Steven C Curry, MDUniversity of Arizona College of Medicine – PhoenixBanner – University Medical Center PhoenixPhoenix, AZ@SteveCurryMD Robert A Robergs, Ph.D.School of Exercise and Nutrition Sciences, Faculty of HealthQueensland University of TechnologyBrisbane, QLD, Australia **NEW** – When finished with this first part, […]
EMCrit Podcast 45 – Acid Base: Part II
This second lecture discusses a quantitative approach to acid base management. I lay out the formula I use to approach an acid-base problem.
EMCrit Podcast 44 – Acid Base: Part I
This lecture discusses a quantitative approach to acid base management. This is also known as the Fencl-Stewart approach, the strong-ion approach or the physicochemical approach. It provides explanations for why acid base disorders occur in human pathophysiology.
EMCrit Podcast 13 – Trauma Resus II: Massive Transfusion
On this podcast, I recap from last show, especially the concept of bare minimum normotension (called erroneously permissive hypotension by just about everyone else) and why we should keep the MAP higher if there is suspected elevations in intracranial pressure I then talk about massive transfusion. This is probably the best strategy for a patient […]