general description Hydroxychloroquine is typically used for treatment of malaria, SLE, or rheumatoid arthritis. It has anti-viral activity in vitro, as well as anti-inflammatory activities. mechanism of action appears similar Multiple mechanisms of anti-viral activity, including: Interference with the cellular receptor ACE2 (potentially making it particularly effective against SARS and COVID-19). Impairment of acidification of […]
COVID Links
Hopkins COVID Map Stanford COVID Evidence Page Rural Environs CrisisEM
How to configure viral filters on a CPAP or BiPAP circuit
I’ve received several questions on twitter about this. There are a variety of ways to do it, depending on available materials… (1) Filter attached directly to the mask The simplest way to achieve this is to attach the filter directly to the mask, as shown below. This should work well – provided that the filter […]
COVID19 Pulm Fellows Seminar
ESICM Seminar on COVID Ventilation Subtypes of COVID Mild Silent Hypoxemia (can cause iatrogenic injury) Indolent Fine then Not (Intubated or Not-Inflammatory Markers) Hyperacute Cytokine Storm / Hemophagocytic Lymphohistiocytosis (HLH) / DIC PathoPhys Loss of hypoxic vasoconstriction Micro-thrombotic disease Avoidance of Intubation tachypnea, hypoxemia, do not seem to be indication Mental […]
Anecdotal Evidence on EMCrit CPAP Set-Up
I will be posting any relayed cases of use of the EMCrit CPAP set-up here: from an ED Doc 3-25-20 This is such a game changer in my shop. I think it will truly save lives and unnecessary tubes/bed allocation. We used this today successfully on COVID Pt in our ED, with short extension […]
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