IBCC chapter & cast: Allergies to beta-lactam antibiotics

Emerging evidence shows that there is no such thing as a “penicillin allergy” or “cephalosporin allergy.”  Instead, cross-allergic reactions are restricted to much smaller groups of antibiotics that share greater structural similarity.  This opens the door to using beta-lactam antibiotics safely in patients who have had an allergic reaction to one or more of these drugs.