Neuroprognostication following cardiac arrest is one of the most important responsibilities of the ICU team. This process begins as soon as ROSC is achieved, with the avoidance of confounding factors (e.g., sedatives and opioids). An organized, multimodal approach is essential. Incidentally, strategies which are aimed at accurate neuroprognostication will also facilitate early awakening – and as such they are consistent with high-quality critical care in general.
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