CAR-T cell therapy is rapidly expanding as a miraculous therapy for numerous malignancies. However, it also causes a variety of unique and severe side-effects, which frequently cause ICU admission. This chapter explores current approaches to complications including CRS (cytokine release syndrome), HLH (hemophagocytic lymphohistiocytosis), and ICANS (immune effector cell-associated neurotoxicity syndrome). Updates will be needed over time to keep this current – please don't hesitate to add additional information or alerts to fresh articles below.
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- IBCC – CAR-T cell therapy recipient in the ICU - April 25, 2023