Invasive pulmonary aspergillosis was traditionally conceptualized as a rare infection restricted to profoundly immunocompromised patients. However, over the past decade, it's become increasingly clear that invasive aspergillosis can also occur as a nosocomial superinfection among patients who aren't immunocompromised (especially following influenza). This opens a can of worms regarding how to sift out colonization versus invasive infection, among critically ill patients who are usually unable to undergo tissue biopsy.
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The IBCC chapter is located here.
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Josh is the creator of PulmCrit.org. He is an associate professor of Pulmonary and Critical Care Medicine at the University of Vermont.
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Any place for serology in the diagnosis?
Hi, Thanks for sharing such an amazing post. It was very useful and informative as well!