Enormous attention is committed to the control of pain, with much less being directed to the control of nausea. However, nausea and vomiting can be even more distressing than pain. By understanding the receptor pharmacology of various antiemetics, a rational and effective approach is possible.
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The IBCC chapter is located here.
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I don’t think prochlorperazine is OTC in the US. Excellent article otherwise
Correct. Prochlorperazine is prescription-only in the U.S.
Great summary as usual! How about NK-1 receptor anatagonis(eg. aprepitant) for vomiting, a common prophylatic drug for CINV or PONV? Thanks!
I see it used in the hospital as one of the PONV prophylaxis meds (Emend) quite routinely for GI or other ERAS surgeries.
Nice summary.
Do consider adding: buscopan/anticholingeric groups, and other non-pharmacological options: P6 acupressure, a whiff of alcohol swab, etc.