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PulmCrit – ACEP task force on septic shock should replace the Surviving Sepsis Campaign
The critical care community has long been plagued by a series of antiquated, overbearing guidelines created by the Surviving Sepsis Campaign (SSC). The campaign was originally sponsored by Eli Lilly and Edwards Life Sciences, as a commercial marketing campaign. The backbone of the original guidelines was a single center trial by Rivers, which has failed […]
Colchicine: Our Deal with the Devil
by Meghan Spyres January 2021 “Colchicine for Early COVID-19? Trial May Support Oral Therapy at Home” “Health Experts Green-Light Colchicine for Treating Outpatient COVID” “Colcorona: Colchicine Reduces Complications in Outpatient COVID-19” I can say with near certainty that upon reading these headlines, the global toxicology community, my colleagues, and I, all gasped a horrified “Oooohhhhh […]
IBCC – Local Anesthetic Systemic Toxicity (LAST)
Local Anesthetic Systemic Toxicity (LAST) is fortunately extremely rare. However, with the ongoing expansion of nerve blocks and lidocaine infusions in a variety of different contexts, this is likely to be seen more often over time. Prompt recognition and antidotal therapy are essential. The IBCC chapter is located 👉 here. The podcast & comments are […]
IBCC – Calcium channel blocker & beta blocker poisoning
Calcium channel blocker poisoning is one of the most formidable intoxications encountered critical care. As for most topics in toxicology, there is no level-I evidence regarding this. This chapter explores treatment options for beta blocker and calcium channel blocker poisoning, with the admitted limitation that it’s impossible to know which treatments are optimal and in […]
IBCC – Necrotizing Fasciitis
Let’s be honest, necrotizing fasciitis is a perennial source of errors. This is a difficult diagnosis to make. It can be tedious to continually maintain a high level of suspicion for it, but suspicion and early diagnosis are critical. The IBCC chapter is located 👉 here. The podcast & comments are below. Follow us on […]
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