A few weeks ago, I did a Primer episode on Serotonin Syndrome and Neuroleptic Malignant Syndrome. During that episode, I promised to bring on Eelco Wijdicks to discuss his work on NMS.
The Papers
- NEJM Review Paper on NMS
- Neurocritical Care Retrospective Study on NMS
Questions for Eelco
- Why 2 papers on NMS?
- Is this a Neurocrit Care thing at your shop? Should we be involving neurology
- Case series used DSM criteria, is this the best criteria for clinical use?
- No increased muscle tone or rigidity-is NMS ruled out?
- How to differentiate NMS from Neuroleptic-Induced parkinsonism? (30% of patients exposed to anti-psychotics)?
- SS and NMS are always put up there as two competing, easily confused diagnoses, but your paper states the resemblance is superficial. So what separates the two in terms of presentation?
- Severe catatonia is another one mentioned, how does that present in your experience?
Treatment of NMS
- When to intubate?
- When to dantrolene? How long to continue?
- Does bromocryptine and/or amantadine actually work?
- ECT
Eelco's Books
Additional New Information
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Editor-in-Chief, at EMCrit.org
An ED Intensivist from NY.
Professor
Nassau University Medical Center
No conflicts of interest (coi).
Professor
Nassau University Medical Center
No conflicts of interest (coi).
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