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EMCrit 258 – Should Andexxa be added to a Hospital’s Formulary?

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The question of the use of Andexxa, a reversal agent for Factor Xa Inhibitors, has been batting around my brain for a few months now. We are in the unfortunate position of having a drug with very questionable evidentiary support but with an FDA labelled indication. I received an email from the lead author of paper just published in Neurocritical Care.

Dr. Harry Peled is the medical director of Cardiology and Critical Care at St Jude Medical Center in California. Relevantly, he is also chair of the Pharmacy an Therapeutics Committee.

I would love to hear your thoughts on this issue–place them in the comments below.

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Scott Weingart. EMCrit 258 – Should Andexxa be added to a Hospital’s Formulary?. EMCrit Blog. Published on October 26, 2019. Accessed on June 4th 2020. Available at [https://emcrit.org/emcrit/andexxa-formulary/ ].

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