by Jeanna Marraffa A 45-year-old male with history of cardiomyopathy has an out of hospital cardiac arrest. Resuscitative efforts were initiated pre-hospital and return of spontaneous circulation (ROSC) was achieved. However, upon arrival to the emergency department (ED), he was profoundly hypotensive with a blood pressure of 50/palp and a heart rate of 40 beats […]
Tox and Hound – In the Beginning
by Diane Calello Risk Assessment in Acetaminophen Toxicity In the beginning God created the heavens and the earth. Darkness covered the formless earth, wind swept over the waters. And God said, “Let there be acetaminophen”. And so it was. And it was good. Then man discovered acetaminophen and, realizing he was naked without it, covered […]
The Dantastic Mr. Tox & Howard – S02E10 – The Secret Diet of Pets
Exploring the World of Veterinary Toxicology with Dr. Ahna Brutlag Join Dan (@drusyniak) &Howard (@heshiegreshie) as they explore the world of veterinary toxicology with Dr. Ahna Brutlag, Director of Veterinary Services at the Pet Poison Helpline. Find out how the approach to the poisoned veterinary patient is both similar and different to our bipedal brethren. […]
Tox and Hound – Sneaking into the Party
by Sarah Shafer How does a heart break? In the case of beta-blocker (BB) and calcium-channel blocker (CCB) overdose, it’s a lack of calcium. Calcium is essential to muscle contraction, allowing actin and myosin to interact so that the cell shortens. Without calcium, the myosin and actin are blocked from interacting, and the cell stays […]
Tox and Hound – Check Yourself
by Andrew Stolbach The history of cancer therapy is entwined with the history of the 20th and 21st centuries. Scientific discovery does not occur in a historical vacuum. The swirl of world events does not stop outside the laboratory. In 1910, as Viennese researchers Ernest Freund and Gisa Kaminer published observations that some substance in […]
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