PulmCrit (EMCrit)

Cardiac glycoside poisoning continues to be a relevent topic, due to both digoxin and plants containing cardiac glycosides.  As with all things toxicologic, ongoing debate surrounds the precise dosing and indications for anti-digoxin antibody fragments. The IBCC chapter is located 👉 here. The podcast & comments are below. Follow us on iTunes

Poisoning is one of the most common causes of ICU admission.  The vast majority of these patients do fine, with minimal supportive therapy and observation.  However, occasional patients will progress to organ failures and potentially death.  This chapter explores how to approach these patients, with an eye towards identification and prompt treatment of the critically […]

Thrombotic microangiopathy is a rapidly moving target, which has evolved considerably in just the past few years.  Complementopathies (e.g., atypical hemolytic uremic syndrome) probably represent a largely unappreciated, yet critical, dimension of many diseases.  Thrombotic thrombocytopenic purpura (TTP) remains an important hematologic emergency that must be promptly recognized.  This chapter attempts to disentangle these entities, […]

The opioid epidemic has caused us all to become far more familiar with opioid intoxication than we ever wanted to be.  However, some nuances still remain (e.g., management of methadone and loperamide intoxications). The IBCC chapter is located 👉 here. The podcast & comments are below. Follow us on iTunes

Blockade of the fast cardiac sodium channels is an important component of cardiotoxicity due to many intoxicants.  Historically the most common cause of sodium channel blockade has been tricyclic antidepressant poisoning, but a wide variety of xenobiotics can affect the sodium channels.  Fortunately, close attention to the EKG may be sufficient to reach an accurate […]