EMCrit Project

In 2015 I wrote this post on ACEi-induced angioedema.  I still think it was a pretty good post (particularly for 2015), but it’s become increasingly clear recently that the post was fundamentally flawed.  Let’s try to straighten this out.  old model of bradykinin-mediated angioedema This is a conceptual model of how bradykinin-mediated angioedema occurs.  Several […]

The timing of basal insulin administration in DKA has been controversial for years.  I posted the following poll on twitter recently to get a sense of current opinion on this: So, it seems that the majority of people are using traditional management (wait for the anion gap to close, give basal insulin, then shut off […]

Severe hemoptysis is a true challenge.  Due to the rarity of this condition, there is little high-quality data on it.  So you can’t become a hemoptysis whisperer by reading books.  Unfortunately, due to the rarity of the condition it’s also difficult to accumulate clinical experience. 

Since it looks like the United States is about to go into total meltdown from a heat wave, I dusted off the hyperthermia chapter.  This is a bit of an impromptu post, so we don’t have a podcast to go along with it (we will record one eventually – Adam has more experience with the […]

Below is a card from one of the first patients I treated for alcohol withdrawal.  He lingered in the hospital for days on various benzodiazepine regimens (including a lorazepam infusion), and eventually limped home on an oral chlordiazepoxide taper.  He wrote me a thank-you card days after leaving the hospital, but as you can see […]