by Chris Holstege In the practice of medicine at a public university, I often encounter the complaint from my patients that “someone must have slipped something into my drink”. Their rationale is that they have drunk this much on previous occasions, but this time they do not remember anything. I recently was […]
The Dantastic Mr. Tox & Howard Episode 7 – Life is a High-Way
http://traffic.libsyn.com/dantastictox/Dantastic_Tox_S01E07.mp3 Addiction beyond dopamine with Dr. Andy Chambers Join Dan (@drusyniak) &howard (@heshiegreshie) as they explore the neurobehavioral underpinnings of addiction. Learn about the Google Maps of the motivational system of the brain and gain insight into why psychiatric patients and adolescents are such vulnerable populations. And make sure that you check out Dr. Andy […]
Tox and Hound – The Dirty on Dantrolene
by Sarah Shafer Dantrolene is one of the few, true “muscle relaxers”. It was discovered in 1967 and approved by the FDA in 1979. Unlike paralytic neuromuscular blockers, dantrolene works post-synaptically, at the sarcoplasmic reticulum in the myocyte. It binds to the ryanodine receptor in skeletal muscle (RYR1), preventing sarcoplasmic calcium-induced calcium release. When RYR1 […]
The Dantastic Mr Tox & Howard Episode 6 – Can’t Get Enough Fat On Thanksgiving
Join Dan (@drusyniak) &howard (@heshiegreshie) as they talk turkey with Dr. Guy Weinberg (@lipidguy) about intralipid emulsion therapy.
Tox & Hound – Pour Some Octreotide on Me
by Kavita Babu In 1999, a toddler encountered glipizide during an exploratory ingestion. When he wouldn’t wake up from a nap, the family called the EMTs, who found a fingerstick blood sugar of 13 mg/dL. He received several D25 boluses – each time his sugar would respond appropriately, then fall. His care […]