Urosepsis is one of my favorite ICU diagnoses. In almost all cases, patients will improve dramatically within 12-24 hours and leave the ICU with minimal sequelae. But that shouldn’t lull us into a false sense of security: careful antibiotic selection, aggressive resuscitation, and (in some cases) emergent drainage may be required for a good outcome.
Dantastic Live at NACCT 2018 . . . &Howard That’s not a lump of coal in your stocking . . . Join Dan (@drusyniak) &Howard (@heshiegreshie) as they speak with Dr. Dan Rusyniak (@drusyniak) live on stage at the 2018 North American Congress of Clinical Toxicology Pre-Meeting Symposium. Dan cleverly tricked Howard into being the foil […]
by Diane Calello The decision to move from a system in which cannabis is completely illegal, to one in which it is not only legal for recreational use, but also facilitated with government resources, has many implications in many realms. Advocates point to significant gains in the social justice arena and the relative safety of […]
If you haven’t started seeing these yet, you will soon. Checkpoint inhibitors are a form of immunotherapy being used for an increasingly broad range of malignancies. They cause a diverse range of adverse events, due to releasing uncontrolled autoimmune hyperactivity. Clinically this can mimic just about any rheumatologic condition. Fortunately these events are quite treatable. However, a high index of suspicion and prompt therapy is important.
This paper slipped across my twitter feed over the weekend. It was a bit disquieting to see that it was getting a lot of attention, despite being a methodological train wreck (seriously, MedTwitter, where’s the skepticism??). This post will briefly walk through some of the main flaws. There will be a bit of pharmacology, a modicum of methodology, and a lot of ranting.