INTEGRILIN is to be administered by volume according to patient weight. Patients should receive INTEGRILIN according to the following table:

 

 

INTEGRILIN Dosing Charts by Weight Patient Weight 180 µg/kg Bolus Volume 2.0 µg/kg/min Infusion Volume 1.0 µg/kg/min Infusion Volume (kg) (lb) (from 2 mg/mL vial) (from 2 mg/mL 100-mL vial) (from 0.75 mg/mL 100-mL vial) (from 2 mg/mL 100-mL vial) (from 0.75 mg/mL 100-mL vial)  37-41  81-91  3.4 mL 2.0 mL/h  6.0 mL/h 1.0 mL/h  3.0 mL/h  42-46  92-102  4.0 mL 2.5 mL/h  7.0 mL/h 1.3 mL/h  3.5 mL/h  47-53 103-117  4.5 mL 3.0 mL/h  8.0 mL/h 1.5 mL/h  4.0 mL/h  54-59 118-130  5.0 mL 3.5 mL/h  9.0 mL/h 1.8 mL/h  4.5 mL/h  60-65 131-143  5.6 mL 3.8 mL/h 10.0 mL/h 1.9 mL/h  5.0 mL/h  66-71 144-157  6.2 mL 4.0 mL/h 11.0 mL/h 2.0 mL/h  5.5 mL/h  72-78 158-172  6.8 mL 4.5 mL/h 12.0 mL/h 2.3 mL/h  6.0 mL/h  79-84 173-185  7.3 mL 5.0 mL/h 13.0 mL/h 2.5 mL/h  6.5 mL/h  85-90 186-198  7.9 mL 5.3 mL/h 14.0 mL/h 2.7 mL/h  7.0 mL/h  91-96 199-212  8.5 mL 5.6 mL/h 15.0 mL/h 2.8 mL/h  7.5 mL/h  97-103 213-227  9.0 mL 6.0 mL/h 16.0 mL/h 3.0 mL/h  8.0 mL/h 104-109 228-240  9.5 mL 6.4 mL/h 17.0 mL/h 3.2 mL/h  8.5 mL/h 110-115 241-253 10.2 mL 6.8 mL/h 18.0 mL/h 3.4 mL/h  9.0 mL/h 116-121 254-267 10.7 mL 7.0 mL/h 19.0 mL/h 3.5 mL/h  9.5 mL/h >121 >267 11.3 mL 7.5 mL/h 20.0 mL/h 3.7 mL/h 10.0 mL/h