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Richard B Lawson, MB, BCh, Registrar,
Department of Anesthesia, Johannesburg Hospital
Jacques Goosen, MB, ChB, (PRET), FCSSA, Principal
Surgeon and Head, Trauma Unit, Johannesburg Hospital and University of
the Witwatersrand
Updated: Feb 25, 2009
In the 19th century, penetrating abdominal wounds were managed nonoperatively. The associated morbidity and mortality rates were greater than 70%.[1 ]Experience gained during World War I, World War II, and the Korean Conflict led to an aggressive approach of operative management for all penetrating abdominal wounds.[2 ]This approach resulted in an unacceptably high frequency of laparotomy with findings negative for trauma. In 1960, Shaftan developed an approach of selective conservatism for penetrating abdominal injury and revolutionized abdominal stab wound management.[3 ]
The optimal method to determine the need for laparotomy has yet to be definitively established. Abdominal stab wound exploration forms part of a strategy developed by surgeons to allow a more selective approach. In asymptomatic patients with stab wounds to the anterior abdomen, 2 methods are widely used to help determine the need for laparotomy:
The objective is to reduce the number of patients with trivial or no
intraperitoneal injury who are subjected to laparotomy. However, a high
degree of diagnostic accuracy must be maintained to limit the frequency
of missed injury. A reduction in unnecessary hospitalization is also
targeted.
Investigators in this field
are continuing to study other protocols and investigative tools. No
protocol is currently universally accepted. Other modalities that have
been studied include DPL alone, laparoscopy, CT, and ultrasonography.
These strategies of selection for laparotomy are explored in greater
detail below.
Abdominal stab wound
exploration is a safe, rapid, and cost-effective tool in the management
of asymptomatic patients who present with an anterior abdominal stab
wound.[4 ]This approach has no place in the treatment of
patients who are unstable, who have peritonitis, or who have
evisceration. Patients with peritonitis and those who are
hemodynamically unstable should undergo mandatory laparotomy.
More than 25% of anterior abdominal stab wounds do not
penetrate the peritoneal cavity.[5,6 ]Local wound exploration
allows the safe discharge of these patients from the emergency
department. Only half of the wounds that penetrate the peritoneum cause
damage that requires surgical intervention.[1,7 ]The organs
most commonly injured with anterior abdominal stab wounds are the small
bowel, the liver, and the colon. Missed hollow viscus injuries are
associated with significant morbidity and mortality.
The authors advocate abdominal stab wound exploration
in asymptomatic patients who present with an anterior abdominal stab
wound. An exploration with negative findings is reliable and highly
sensitive. Abdominal stab wound exploration combined with further
investigation, such as DPL or serial evaluation, achieves acceptable
specificity rates. Minimizing the time taken to control ongoing
intraperitoneal contamination is critical in penetrating stab wounds,
and local exploration is a valuable first step in speeding up the
decision-making process. When combined with DPL, abdominal stab wound
exploration allows significant injuries that are not immediately
apparent to be identified early.
Wound
exploration can be performed successfully by surgeons or ED personnel
who are trained in the procedure. This strategy aids with patient flow
through a busy emergency department.
Abdominal stab wound exploration is indicated in a patient who presents with a stab wound to the anterior abdomen, normal vital signs, no signs of peritonitis, and no evidence of evisceration.
Abdominal stab wound exploration is contraindicated if immediate
laparotomy is indicated. The situations in which immediate laparotomy is
indicated include the following:
Other contraindications to abdominal stab wound exploration include the following:
Relative contraindications include the following:
For more information, see Local Anesthetic Agents, Infiltrative Administration.
The critical concept is to determine the end point of the tract under
direct vision.
Complications of abdominal stab wound exploration are rare (rate is
approximately 1%). Complications include local wound infection and
bleeding.
Published papers report no
false-negative exploration findings.[5,9 ]
No debate exists about the management of patients who are
hemodynamically compromised or who exhibit peritonitis upon abdominal
examination. These patients are immediately transferred to the operating
room and undergo laparotomy.
The
optimal management for an asymptomatic patient with an anterior
abdominal stab wound remains controversial. Routine laparotomy was once
advocated but is no longer accepted practice. The universally accepted
practice is now selective management of asymptomatic patients with stab
wounds. However, the methods used to select those who will benefit from
laparotomy are controversial.
No
consensus has been reached regarding the treatment of patients with
evisceration of omentum or an abdominal organ. Many still opt for
operative intervention in this group and cite a high incidence of organ
injury as the reason for their standpoint.[10,11 ]Demetriades
and others have shown that these patients can also be successfully
managed nonoperatively, provided that they are stable and that the
findings of their abdominal examination remain benign.[12,13 ]
Methods that aid practitioners in the selection of patients whose injuries are likely to warrant laparotomy are an area of ongoing study. Each method has its merits and shortfalls, and combinations of techniques are not uncommon.
The 2 most commonly used selective approaches are abdominal stab wound exploration (combined with DPL) and serial clinical evaluation. Results from the available studies show comparable patient outcomes.
Modern approaches have succeeded in limiting the mortality due to anterior abdominal stab wounds to as low as 0-3.6%.[1,14 ]Selective approaches have achieved unnecessary laparotomy rates of less than 10%.[1,4,6,9,12,14 ]In abdominal stab wounds, the morbidity rate of a laparotomy with negative findings is in the range of 1.5-8%.[14,15,16 ]Regrettably, a limited number of injuries are still missed.
Abdominal stab wound exploration
Abdominal stab wound exploration allows for safe and immediate discharge of approximately 25% of patients with an abdominal stab wound. When performed by trained operators, this procedure is 100% sensitive.[9 ]If one considers patients who mandate laparotomy and those who have an exploration with negative findings, local wound exploration can guide an early, clear, and safe decision in more than half of patients who present with an anterior stab wound.[9 ]Unfortunately, positive local wound exploration findings carry a poor specificity for significant intra-abdominal injury. If all patients with positive abdominal exploration findings were to undergo laparotomy, more than 40% would do so unnecessarily.[1,9 ]Patients with positive local exploration findings, therefore, undergo DPL to further select those who are likely to have an intra-abdominal injury that requires surgical intervention. This strategy successfully reduces the number of nontherapeutic laparotomies.[17 ]
Diagnostic peritoneal lavage
DPL was initially developed as a tool to help assess for intra-abdominal injury in patients who had sustained blunt trauma. Its value in penetrating trauma is accepted, but its application is less clear. No consensus exists concerning what constitutes a positive result, and protocols vary from one institution to the next. Pre-lavage aspiration of 20 mL of blood is generally accepted as a positive result. The lavage fluid is assessed for red blood cells, white blood cells, bile, feces, and vegetable matter.
Some authors have also assessed various enzymes, including alkaline phosphatase (ALP) and amylase, with limited clinical value. Some authors have used a red blood cell count of greater than 100,000/μL and a white blood cell count of greater than 500/μL as the threshold. At these relatively high values, the incidence of missed injury increases and, consequently, even patients with negative lavage findings are further assessed and observed.[4,6,14 ]These cell count cutoff values are the same as those used for blunt trauma. When applied, these values achieve an accuracy rate of 90-91%.[4,18 ]
Isolated injuries to hollow organs often cause little bleeding. These injuries are commonly associated with lavage red blood cell counts of less than 100,000/μL or even of less than 10,000/μL. However, red cell counts of less than 1,000/μL are almost never associated with significant intra-abdominal injury.[4,9,19 ]
The white blood cell count threshold is not without problems, either. An elevated count raises suspicion of a hollow visceral injury. The intraperitoneal contents do not reliably produce a white cell response to injury until approximately 3 hours after the injury occurs. Hence, the timing of the lavage becomes important. Lavages performed soon after injury may reflect relatively low white cell counts despite significant injury. If significant delay occurs before the lavage is performed, even a simple breach of the peritoneum may produce a significantly raised white blood cell count.[4 ]
No threshold for DPL achieves 100% accuracy. The clinician must
determine the relative weight of missed injury (false-negative findings)
versus that of unnecessary laparotomy (false-positive findings). Up to
60% of visceral injuries involve the small bowel or colon.[1,20 ]Injuries
to these organs are still the leading cause of morbidity and mortality
in patients with abdominal stab wounds.[9 ]Surgeons are aware
that the risk of morbidity and mortality of missed hollow visceral
injury far outweighs that of unnecessary laparotomy; therefore, many
have elected to lower their threshold for operative intervention. DPL is
increasingly considered a quantitative assay that merely serves to
provide further information to assist in decision-making and should no
longer be used blindly with absolute cutoff values.
DPL may be unhelpful in patients with retroperitoneal
injury. A lower threshold increases the sensitivity of the investigation
but results in an increase in unnecessary surgery.[21 ]Demetriades
achieved successful nonoperative management of patients with solid
viscus injury with a protocol combining serial observation and CT scan.[22
]DPL is not organ-specific. Oreskovich and Carrico quote a
complication rate for DPL of less than 1%.[9 ]
Serial clinical evaluation
Serial clinical evaluation is a method used by many surgeons as a selective approach to abdominal stab wound management. Approximately 30% of patients with a significant abdominal injury have initial benign abdominal examination findings.[1 ]Furthermore, up to 10% of injuries are initially overlooked, even in the more advanced trauma centers.[23 ]These statistics clearly demonstrate the value of serial evaluation.
The length of hospital stay in patients whose injuries are managed
conservatively varies among institutions. One study showed that no
significant injuries were discovered in any patients who were
asymptomatic after 12 hours of observation.[24 ]Most
protocols, however, recommend evaluation of the patient over 24-72
hours.[12,25,26 ]The delay in laparotomy inherent in such an
approach has not been associated with adverse outcome.[12 ]This
is, possibly, because most severe injuries are obvious early. Degree of
contamination is likely more important than the delay in surgery,
provided the delay is not excessive. However, few would argue with the
principle that the time taken to control contamination should be
minimized. Martin et al found a 6-fold increase in complications in
patients with colonic injury who were not operated on within 12 hours.[27
]
Unfortunately, studies have
also shown that 14-28% of patients without an injury that penetrates the
peritoneum have misleading positive abdominal examination findings.[6,14,15
]
Other methods of selection
Other methods of selection have been advocated, but few claim
advantage over the 2 selective approaches discussed above.
Some authors advocate DPL alone without prior local
wound exploration as particularly useful in patients who are difficult
to assess clinically because of drugs or alcohol or who are to be
anesthetized for another procedure. A study successfully used a red
blood cell lavage count of less than 1,000/μL as a criterion for
immediate discharge from the emergency department.[19 ]The
authors claim that DPL is a simple procedure with few complications and
that the complications, when they occur, are usually immediately
evident. This view is certainly not shared by all.
Sinography ("stabogram") and blind probing of wounds
are unreliable procedures.[1,28 ]
Few authors advocate the use of laparoscopy in the management of
anterior abdominal stab wounds. It may be useful as an adjunct in
special circumstances. Laparoscopy is reliable when used to determine
breach of the peritoneum or to assess potential diaphragm injuries in
patients with wounds to the left upper quadrant or lower chest. It is
unreliable in the assessment of hollow visceral injuries. A protocol of
stab wound exploration followed by emergency department awake
laparoscopy for equivocal cases has been studied, but it resulted in
31.3% of selected patients being exposed to the risks of unnecessary
surgery.[29 ]At this stage, laparoscopy lacks sufficient
therapeutic value to be used routinely in abdominal stab wounds.[30
]
Ultrasonography, on its own, is
inadequate as an investigation of anterior abdominal stab wounds and
rarely aids in the management of these cases.[31 ]Focused
abdominal sonography for trauma (FAST) scan has proved to be a reliable
method of investigation in blunt abdominal trauma, especially when the
scan is repeated.[32 ]This type of scan is less helpful in
the assessment of patients with penetrating injury.[31,33 ]Low
sensitivity and low negative predictive value limit its accuracy as an
investigation. Positive FAST scan findings are useful predictors of
significant intraperitoneal injury and, when performed early, can
decrease the time to operation.[33 ]To confidently exclude
significant intraperitoneal injury in patients with negative FAST scan
findings, additional investigations are required.[33 ]
A small study of 35 patients has suggested a role for
fascial ultrasonography to detect fascial penetration in anterior
abdominal stab wounds.[34 ]As an investigation, fascial
ultrasonography had a specificity and positive predictive value of 100%.
Positive fascial ultrasonographic findings rule out the need for an
abdominal stab wound exploration. Unfortunately, even in more
experienced hands, fascial ultrasonography had a sensitivity of only
73%. The resultant drawback, therefore, is that negative fascial
ultrasonographic findings do not adequately exclude an intra-abdominal
injury, which requires further investigation or observation. Further
assessment of the use of fascial ultrasonography may be justified.
Despite the instrumental role of CT scan in the assessment of
penetrating flank and back wounds, it has traditionally been of little
help with anterior abdominal wounds. The technology has not adequately
revealed hollow visceral and diaphragm injuries.[35 ]Interestingly,
the presence of free intraperitoneal air has poor specificity for
intra-abdominal organ injury. Air can track through a defect in the
abdominal wall and enter the peritoneal cavity. As part of a prospective
study of 651 patients with abdominal stab wounds, 18 patients with free
air under the diaphragm on plain radiograph were managed conservatively
by method of serial examination. Only 2 of these patients went on to
laparotomy, and no adverse outcomes were reported in the other 16
patients.[12 ]
With improved technology, CT scan may
be becoming a more useful study for penetrating abdominal wounds. More
recent studies find fewer missed hollow visceral injuries than was
previously reported.[22,36 ]Serial clinical evaluation, when
combined with CT scan, has been shown to be an effective strategy in the
selective management of abdominal stab wounds.[22,36 ]This
approach is only suitable for well-staffed major centers with sufficient
experience in abdominal stab wound management.
Further developments
Further trials (or, perhaps, technology) may provide the next
development in anterior abdominal stab wound management. No meaningful
change has occurred in decades in the suggested management of this
important and growing group of patients. No single investigation is
likely to provide all the information necessary to accurately determine
which patients are likely to have injuries that require surgical
intervention. The combination of physical examination and other
investigations has allowed a reduction in unnecessary intervention.[37
]
A multidisciplinary working
party recently developed evidence-based guidelines for the management of
haemodynamically stable patients with stab wounds to the anterior
abdomen. They conducted a systematic review of the available literature
and recommended the use of abdominal stab wound exploration.[38 ]
For now, abdominal stab wound exploration remains a
valid and effective tool that allows safe and early discharge of a
significant number of patients. It is also valuable as a first step in a
process that limits the time to decision-making in the management of
asymptomatic patients with anterior abdominal stab wounds.
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Oreskovich MR, Carrico CJ. Stab wounds of the anterior abdomen. Analysis of a management plan using local wound exploration and quantitative peritoneal lavage. Ann Surg. Oct 1983;198(4):411-9. [Medline].
Burnweit CA, Thal ER. Significance of omental evisceration in abdominal stab wounds. Am J Surg. Dec 1986;152(6):670-3. [Medline].
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abdominal stab wound exploration, local wound exploration, LWE, rectus fascia, rectus sheath, transversus abdominis muscle, transverse abdominal muscle, back stab wound, flank stab wound, stabbing, penetrating wound, nonpenetrating wound, penetrating abdominal trauma, diagnostic peritoneal lavage, DPL, peritoneal wound, midline wound, lateral wound, wound exploration, laparotomy
Richard B Lawson, MB, BCh, Registrar, Department of
Anesthesia, Johannesburg Hospital
Richard B Lawson, MB,
BCh is a member of the following medical societies: South African
Medical Association
Disclosure: Nothing to disclose.
Jacques Goosen, MB, ChB, (PRET), FCSSA, Principal
Surgeon and Head, Trauma Unit, Johannesburg Hospital and University of
the Witwatersrand
Disclosure: Nothing to disclose.
Mary L Windle, PharmD, Adjunct Assistant Professor,
University of Nebraska Medical Center College of Pharmacy, Pharmacy
Editor, eMedicine
Disclosure: Pfizer
Inc Stock Investment from financial planner; Avanir Pharma Stock Investment
from financial planner ; WebMD Salary and stock Employment and
investment from financial planner
Luis M Lovato, MD, Associate Clinical Professor,
David Geffen School of Medicine at UCLA; Director of Critical Care,
Department of Emergency Medicine, Olive View/UCLA Medical Center
Luis M Lovato, MD is a member of the following medical societies: Alpha
Omega Alpha, American College of Emergency Physicians, and Society for
Academic Emergency Medicine
Disclosure: Nothing to disclose.
Gil Z Shlamovitz, MD, Assistant Professor of
Emergency Medicine, University of Connecticut School of Medicine;
Attending Physician, Emergency Department, Windham Community Memorial
Hospital, Willimantic, CT; Attending Physician, Emergency Department,
Hartford Hospital, Hartford, CT
Gil Z Shlamovitz, MD is
a member of the following medical societies: American Academy of
Emergency Medicine and American College of Emergency Physicians
Disclosure: Nothing to disclose.
Erik D Schraga, MD, Consulting Staff, Department of
Emergency Medicine, Mills-Peninsula Emergency Medical Associates;
Consulting Staff, Permanente Medical Group, Kaiser Permanente, Santa
Clara Medical Center
Disclosure: Nothing to disclose.
Hannah Swart, Switch Design, South Africa, for the
illustrations.
Johannesburg
Hospital Trauma Unit, for assistance in obtaining material for
the article.
Cayton CG, Nassoura ZE. Abdomen. In: Ivatury RR, Cayton CG, editors. Textbook
of Penetrating Trauma. 1st ed.
Baltimore, Md: Williams & Wilkins, 1996:281-299.
Kirby R, Viswanathan S, Jiang R. Diagnostic and
Therapeutic techniques. In: Sherry E, Trieu L, Templeton J, editors. Trauma.
1st ed. New York:
Oxford University Press, 2003. p.715-716.
Back and flank wounds
Coppa GF. Back and Flank. In: Ivatury RR, Cayton CG,
eds. Textbook of
Penetrating Trauma. 1st ed.
Baltimore, Md: Williams & Wilkins, 1996:300-308.
Diagnostic peritoneal lavage
Marx J. Diagnostic Peritoneal Lavage. In: Ivatury RR,
Cayton CG, editors. Textbook
of Penetrating Trauma. 1st ed.
Baltimore, Md: Williams & Wilkins, 1996:335-343.
Wilson RF, Walt AJ. General Considerations in Abdominal
Trauma. In: Wilson RF, Walt AJ. Management
of Trauma: Pitfalls and Practice. 2nd ed.
Baltimore, Md: Williams & Wilkins; 1996:411-431/20.
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